Vampire queen Mina Tepes has suffered an attack from nano-technology. As the Bund's security teams deal with this latest threat, an even bigger terror strikes: a mysterious new assassin who wields a power greater than even Akira's lycanthropic abilities. While Akira hunts the enigmatic assassin down, Akira's own dark past is revealed, creating a schism between Akira and Mina that may never heal.